M Nawano Selected Research

T 1095

5/2001	Inhibitory effect of hyperglycemia on insulin-induced Akt/protein kinase B activation in skeletal muscle.
1/2001	Improved diabetic syndrome in C57BL/KsJ-db/db mice by oral administration of the Na(+)-glucose cotransporter inhibitor T-1095.
3/2000	Antidiabetic effect of T-1095, an inhibitor of Na(+)-glucose cotransporter, in neonatally streptozotocin-treated rats.
3/2000	Hyperglycemia contributes insulin resistance in hepatic and adipose tissue but not skeletal muscle of ZDF rats.

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M Nawano Research Topics

Disease

3	Hyperglycemia 05/2001 - 03/2000
3	Insulin Resistance 05/2001 - 03/2000
1	Type 2 Diabetes Mellitus (MODY) 01/2001
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2001
1	Diabetes Complications 01/2001
1	Albuminuria 01/2001
1	Body Weight (Weight, Body) 01/2001
1	Glucose Intolerance 01/2001

Drug/Important Bio-Agent (IBA)

4	T 1095IBA 05/2001 - 03/2000
3	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 05/2001 - 03/2000
3	Insulin (Novolin)FDA Link 05/2001 - 03/2000
2	Glucose (Dextrose)FDA LinkGeneric 01/2001 - 03/2000
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 05/2001
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 05/2001
1	Streptozocin (Streptozotocin)FDA Link 05/2001
1	Blood Glucose (Blood Sugar)IBA 01/2001
1	Therapeutic UsesIBA 01/2001
1	benzofuranIBA 01/2001
1	PhlorhizinIBA 01/2001
1	KetonesIBA 03/2000
1	Nonesterified Fatty Acids (NEFA)IBA 03/2000
1	SodiumIBA 03/2000
1	GurIBA 03/2000